Email: apborgesfe.up.pt

Phone: +351 22 041 4968

Room: INESC 4.9

Laboratory: E007

Senior Researcher

Member of the Scientific Steering Committee

Research group: Biotechnology

Research position: Assistant Researcher

Background: PhD in Chemical and Biological Sciences - University of Trás-os-Montes and Alto Douro, Portugal

Anabela Borges

Major research topics

• Bacterial resistance to antimicrobial agents
• Bioprospecting of new phytochemical molecules with antimicrobial activity
• Development of novel strategies of biofilm control based on phytochemicals
• Looking for new quorum-quenching compounds and virulence attenuators
• Design and synthesis of bioactive molecules by tailored structural modification
• Molecular Docking studies

Selected Publications

Baptista, J., Simões, M., Borges, A. (2018). Effect of plant-based catecholic molecules on the prevention and eradication of Escherichia coli biofilms: a structure activity relationship study. International Biodeterioration & Biodegradation, In Press (DOI: 10.1016/j.ibiod.2018.02.004).

Borges, A., Sousa, P., Gaspar, A., Vilar, S., Borges, F., Simões, M. (2017). Furvina inhibits 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes. Biofouling, 33(2):156-168.

Borges, A., Abreu, A. C., Dias, C., Saavedra, M. J., Borges, F., Simões, M. (2016). New perspectives on the use of phytochemicals as an emergent strategy to control bacterial infections including biofilms. Molecules, 21(877):1-41.

Borges, A., Saavedra, M. J., Simões, M. (2015). Insights on antimicrobial resistance, biofilms and the use of phytochemicals as new antimicrobial agents. Current Medicinal Chemistry, 22(21):2590-614.

Borges, A., Ferreira, C., Saavedra, M. J., Simões, M. (2013). Antibacterial activity and mode of action of ferulic and gallic acids against pathogenic bacteria. Microbial Drug Resistance, 19(4):256-265.

Borges, A., Saavedra, M. J., Simões, M. (2012). The activity of ferulic and gallic acids in biofilm prevention and control of pathogenic bacteria. Biofouling, 28(7):755–767.

Selected Projects

“Biocide_for_biofilm - Desenvolvimento de novas soluções biocidas para o controlo efetivo de biofilme” (POCI-01-0145-FEDER-030219), funded by Portuguese Foundation for Science and Technology (FCT). Beginning: 2018. Duration: 36 months. Role: Team member.

“ABFISH - Desenvolvimento de novos antibióticos para aquacultura” (POCI-01-0145-FEDER-028397), funded by Portuguese Foundation for Science and Technology (FCT). Beginning: 2018. Duration: 36 months. Role: Team member.

“Phytodisinfectants - Disinfection of planktonic bacteria and biofilms in hospital settings with phytochemical products” (PTDC/DTP-SAP/1078/2012|FCOMP-01-0124-FEDER-028765), funded by Portuguese Foundation for Science and Technology (FCT). Beginning: 2013. Duration: 36 months. Role: Team member.