Idalina Machado

Junior Researcher

Research group: Biotechnology

Background: PhD in Chemical and Biological Engineering – University of Minho, Portugal

Major research topics

• Biofilm formation and control
• Antimicrobial Agents – Biocides and antibiotics
• Emerging biocidal compounds
• Bacterial resistance; Adaptive resistance
• Gel-based proteomics
• Protein expression in stressful conditions

Selected Publications

Sousa-Silva, M., Simões, M., Melo, L., Machado, I., “Pseudomonas fluorescens tolerance to benzyldimethyldodecyl ammonium chloride: altered phenotype and cross-resistance”, Journal of Global Antimicrobial Resistance, (2018), 15, 188-195.

Araújo, P., Machado I., Meireles A., Leiknes T., Mergulhão F., Melo L., Simões M., “Combination of selected enzymes with cetyltrimethylammonium bromide in biofilm inactivation, removal and regrowth”, Food Research International, (2017), 965, 101-107.

Sampaio, J., Machado, D., Gomes, A. M., Machado, I., Santos, C., Lima, N., Martins, M. “Deciphering the Contribution of Biofilm to the Pathogenesis of Peritoneal Dialysis Infections: Characterization and Microbial Behaviour on Dialysis Fluids”, PLoS ONE, (2016), 11 (6).

Meireles, A., Machado, I., Fulgêncio, R., Mergulhão, F., Melo, L., and Simões, M. “Efficacy of antimicrobial combinations to reduce the use of sodium hypochlorite in the control of planktonic and sessile Escherichia coli”. Biochemical Engineering Journal, (2015), 104, 115-122.

Machado I., Coquet L., Jouenne T., and Pereira M. O.. “Proteomic approach to Pseudomonas aeruginosa adaptive resistance to benzalkonium chloride” Journal of Proteomics, (2013), 89, 273-279.

Machado I., Lopes S., Sousa A.M., Pereira M.O.. “Adaptive response of single and binary Pseudomonas aeruginosa and Escherichia coli biofilms to benzalkonium chloride”, Journal of Basic Microbiology, (2011), 51,1-10.

Selected Projects

Biocide_for_Biofilm - Development of novel biocide solutions for effective biofilm control”, funded by FCT. Beginning. 2018. Duration 36 months. Role: Researcher.

POMACEA - Affordable technology for mitigation of membrane (bio)fouling through optimization of pre-treatment and cleaning methods (Inn-INDIGO/0001/2014), funded by FCT. Beginning. 2015. Duration 36 months. Role: Researcher.

SUSCLEAN - Sustainable Cleaning and Disinfection in Fresh-Cut Food Industries (project number: 287514), funded by FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology. Beginning. 2012. Duration 36 months. Role: Researcher.

QUAFETY - Comprehensive Approach to Enhance Quality and Safety of Ready to Eat Fresh Products, funded by FP7-KBBE - Specific Programme " Food Safety of Fresh Products. Beginning. 2012. Duration 36 months. Role: Researcher.

ANTIPEP – Control of Microbial adhesion and biofilm formation on abiotic medical surfaces through antimicrobial peptides-based products (PTDC/SAU-SAP/113196/2009), funded by FCT. Beginning. 2009. Duration 36 months. Role: Researcher.