Rita Sobral Santos

Junior Researcher

Research group: Biotechnology

Background: Joint PhD in Biological and Chemical Engineering (FEUP, Portugal) and in Pharmaceutical Sciences (Ghent University, Belgium)

Major research topics

• Fluorescence in situ hybridization
• Infectious diseases
• Nanomedicine
• Drug delivery
• Biological barriers

Selected Publications

Santos, R. S., Figueiredo, C., Azevedo, N. F., Braeckmans, K., et al. (2017) Nanomaterials and molecular transporters to overcome the bacterial envelope barrier: towards advanced delivery of antibiotics. (In Press). Advanced Drug Delivery Reviews.

Santos, R. S., Dakwar, G.R., Zagato, E., Brans, T., et al. (2017) Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic liposomes in the presence of gastric mucus. Biomaterials.

Santos, R.S., Dakwar, G.R., Xiong, R., Forier, K., et al., (2015). Effect of Native Gastric Mucus on in vivo Hybridization Therapies Directed at Helicobacter pylori. Molecular Therapy - Nucleic Acids.

Santos, R. S., Guimarães, N., Madureira, P. and Azevedo N. F. (2014). Optimization of a Peptide Nucleic Acid Fluorescence in situ Hybridization (PNA­FISH) Method for the Detection of Bacteria and Disclosure of a Formamide Effect. Journal of Biotechnology.

Santos, R. S., Lima, C. C., Carvalho, D., Azevedo, N. F. (2017) Response surface methodology to optimize peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) in Saccharomyces cerevisiae. LWT- Food Science and Technology.

Selected Projects

DelNAM - Strengthening the Research Area of Delivery of Nucleic acid mimics (NAMS) into bacteria to fight the antibiotic crisis - WIDESPREAD-05-2017. Duration 2018-2021; Role: Project manager