Junior Researcher

Research group: Supramolecular Assemblies

Background: PhD in Chemical and Biological Engineering from the University of Porto, Portugal

Stéphanie Andrade

Major research topics

• Production and characterization of nanoparticles for biomedical applications
• Targeted drug delivery to fight brain diseases and antimicrobial resistance
• Evaluation of the safety of nanoparticles in animal models
• Biomimetics membrane models for drug-membrane interaction studies
• Conformational studies of amyloidogenic peptides

Selected Publications

Andrade, S., Ramalho, M., Santos, S., Melo, L., Santos, R., Guimarães, N., Azevedo, N., Loureiro, J., Pereira, M. “Fighting Methicillin-Resistant Staphylococcus aureus with Targeted Nanoparticles”. International Journal of Molecular Sciences, (2023), 24(10), 9030.

Andrade, S., Ramalho, M., Loureiro, J., Pereira, M. “Transferrin-functionalized liposomes loaded with vitamin VB12 for Alzheimer's disease therapy”. International Journal of Pharmaceutics, (2022), 626, 122167.

Andrade, S., Loureiro, J., Ramirez, S., Catumbela, C., Soto, C., Rodrigo, M., Pereira, M. “Multi-Dose Intravenous Administration of Neutral and Cationic Liposomes in Mice: An Extensive Toxicity Study”, (2022), 15(6), 761.

Andrade, S., Loureiro, J., Pereira, M. “Caffeic acid for the prevention and treatment of Alzheimer's disease: The effect of lipid membranes on the inhibition of aggregation and disruption of Aβ fibrils”. International Journal of Biological Macromolecules, 2021, 190, 853–861.

Andrade, S., Loureiro, J., Pereira, M. “The Role of Amyloid β-Biomembrane Interactions in the Pathogenesis of Alzheimer's Disease: Insights from Liposomes as Membrane Models”. ChemPhysChem, 2021, 22(15), 1547–1565.

Selected Projects

“Engineered nano-based device for glioblastoma multiforme therapy” (M-ERA-NET3/0001/2021), funded by FCT. Beginning: 2022. Duration 36 months. Role: Researcher.

“Nanotech-double functionalized particles to transport Nucleic Acid Mimics against Staphylococcus Aureus” (EXPL/NAN-MAT/0209/2021), funded by FCT. Beginning: 2022. Duration 16 months. Role: Researcher.

Email:

stephaniefe.up.pt

Phone: +351 22 041 4855

Room: E221

Laboratory: E205